Probeltebio has developed Mediteanox®, a natural extract obtained from olive (Olea europaea) grown in Spain. Mediteanox® is obtained by their own patented technology, using extraction procedures based on ultrapure water.


Active Principle

Mediteanox® is a unique combination of olive polyphenols, including hydroxytyrosol (HT), a potent natural antioxidant. Olive polyphenols are the only ingredient, outside the vitamins and minerals category, with a EU health claim granted for the antioxidant function: “The polyphenols present in olive oil contribute to the protection of blood lipids, LDL-cholesterol, against oxidative stress.” In order to support this statement, the daily intake should be at least 5 mg of hydroxytyrosol and its derivatives in olive oil. The application of HT in edible oils and soft gelatin capsules capable of contributing to the protection of blood lipids from oxidative damage (oxidation of LDL cholesterol represents a key event in the development of atherosclerosis) has been protected by Probeltebio through patents EP2170090 and US9132104.


Safety And Quality

In the field of food safety, we have the certifications UNE EN ISO 22000, and to a higher level the FSSC 22000, for the production of Mediteanox®. Comprehensive control plan guaranteeing compliance with the legal levels of potential contaminants: pesticides, heavy metals, HPA’s, etc. Claims: Free from organic solvents, GMOs, allergens, BSE, non-irradiated, etc…



Inclusion in food supplements, foods, nutraceuticals, cosmetics and pharmaceuticals. Optimal dose of 5 to 10 mg HT/day depending on the application.